Corticobasal syndrome (CBS) is a clinically defined syndrome with progressive movement and cortical dysfunction, caused by various underlying pathologies, most commonly tau-predominant pathologies such as progressive supranuclear palsy and corticobasal degeneration, or Alzheimer’s disease (AD). Lewy-type α-synucleinopathies (LTS), TDP-43 proteinopathies, and mixed pathologies may also underlie CBS. The clinical impact of these pathologies remains poorly understood.A Biomarker-Based Classification of Corticobasal Syndrome
Corticobasal syndrome (CBS) is a clinically defined syndrome with progressive movement and cortical dysfunction, caused by various underlying pathologies, most commonly tau-predominant pathologies such as progressive supranuclear palsy and corticobasal degeneration, or Alzheimer’s disease (AD). Lewy-type α-synucleinopathies (LTS), TDP-43 proteinopathies, and mixed pathologies may also underlie CBS. The clinical impact of these pathologies remains poorly understood.
In 2026, Brain Support Network’s LBD, PSP/CBD, and MSA caregiver support group meetings will take place on the second Sunday of each month, with the exception of May, 5-6:30pm. The meetings are open 
On August 28, 2025, Stanford’s CurePSP Center for Care and Brain Support Network co-hosted a webinar providing an overview of progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD).